What is meant by the conformation of a protein quizlet?

What is meant by the conformation of a protein quizlet?

Protein Conformation. Overall 3D shape which is crucial to the function, an important property of proteins is the ability to change their conformation, the opening and closing of cell membrane pores.

What might cause a protein to become nonfunctional quizlet?

Temperature, pH, Salt concentration and heavy metals can cause proteins to become denatured (break bonds). Fibrous proteins lose structural strength and globular proteins become insoluble and inactive.

Why is a protein’s conformation important?

Protein conformation is of paramount importance in understanding biomolecular interactions. In the simplest scenario, two molecules may interact with no change in their conformation, as in the key-and-lock model. Molecular interactions that involve conformational changes in the interacting molecules are more versatile.

What function do proteins perform when they speed up biological reactions?

Enzymes are proteins, and they make a biochemical reaction more likely to proceed by lowering the activation energy of the reaction, thereby making these reactions proceed thousands or even millions of times faster than they would without a catalyst. Enzymes are highly specific to their substrates.

What are two possible conformations of a protein?

There are two possible conformations of the planar peptide bond: in the trans peptide group, the Cα atoms are on opposite sides of the peptide bond (Figure 3a ) and in the cis peptide group, the Cα atoms are on the same side of the peptide bond (Figure 3b ).

What is the conformation of a protein?

Protein conformation may be defined as the arrangement in space of its constituent atoms which determine the overall shape of the molecule. The conformation of the protein arises from the bonding arrangements within its structure (Figure 4.3).

What might happen if a protein has a change in one amino acid?

What might happen if a protein has a change in one amino acid? The protein has a new shape. The protein can no longer function properly. The amino acid chain folds incorrectly.

What causes changes in protein structure?

Proteins change their shape when exposed to different pH or temperatures. The body strictly regulates pH and temperature to prevent proteins such as enzymes from denaturing. Some proteins can refold after denaturation while others cannot.

Which protein structure is most important?

primary structure
The primary structure is the most important. If an amino acid is missing or out of sequence, it may cause the succeeding levels to fold differently. Most genetic diseases are caused by malformed proteins.

What are the steps for protein synthesis?

Protein synthesis is the process in which cells make proteins. It occurs in two stages: transcription and translation. Transcription is the transfer of genetic instructions in DNA to mRNA in the nucleus. It includes three steps: initiation, elongation, and termination.

What are the three main stages of protein synthesis?

It includes three steps: initiation, elongation, and termination. After the mRNA is processed, it carries the instructions to a ribosome in the cytoplasm.