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What is the difference between hemolytic and obstructive jaundice?
The most common cause of pre-hepatic jaundice is hemolytic anemia which causes excess heme breakdown. In post-hepatic jaundice or obstructive jaundice, there is an impediment to the flow of bile due to a partial or complete obstruction of the extrahepatic biliary passage between the liver and duodenum.
What is hemolytic jaundice?
Hemolytic jaundice, congenital: Known also as hereditary spherocytosis (HS), this is a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice (yellowing) and splenomegaly (enlargement of the spleen). In HS the red cells are smaller, rounder, and more fragile than normal.
What are the 3 types of jaundice?
There are three main types of jaundice: pre-hepatic, hepatocellular, and post-hepatic.
Which antibiotic is best for jaundice?
We recommend that all patients receiving co-amoxiclav and flucloxacillin should be counselled before the therapy regarding the potential risk of jaundice and that an alternative antibiotic to co-amoxiclav is used if possible in men over the age of 60 years.
What is the treatment for hemolytic jaundice?
In cases of immune hemolytic jaundice, intravenous immunoglobulin therapy may be used to treat the condition. Administration of intravenous immunoglobulin can block monocyte Fc-receptors, preventing or reducing further hemolysis.
What is the main cause of jaundice?
Jaundice happens when there’s too much bilirubin, a yellow-orange substance, in your blood. It’s found in your red blood cells. When those cells die, the liver filters it from the bloodstream. But if something’s wrong and your liver can’t keep up, bilirubin builds up and can cause your skin to look yellow.
What is the most common cause of jaundice?
Excess bilirubin (hyperbilirubinemia) is the main cause of jaundice. Bilirubin, which is responsible for the yellow color of jaundice, is a normal part of the pigment released from the breakdown of “used” red blood cells.