What is laryngeal scleroma?

What is laryngeal scleroma?

Abstract. Respiratory scleroma is a chronic, progressive granulomatous disease of the respiratory tract. The causal organism is the Klebsiella rhinoscleromatis. The disease has three stages: the initial catarrhal stage, granulomatous stage, and sclerotic stage.

What are mikulicz cells?

Medical Definition of Mikulicz cell : a round or oval macrophage with a small nucleus that is found in the nodules of rhinoscleroma and contains the causative bacterium (Klebsiella rhinoscleromatis)

What is Laryngocele?

Introduction. A laryngocele is an abnormal dilation of the laryngeal saccule that extends upward within the false vocal fold, is filled with air, and is in communication with the laryngeal lumen [1, 2].

What causes Rhinoscleroma?

Introduction: Rhinoscleroma is a chronic granulomatous infectious disease, caused by the bacterium Klebsiella rhinoscleromatis. Affects the respiratory tract mucosa, more frequent in the nose.

What is nasal Rhinoscleroma?

Rhinoscleroma, is a chronic granulomatous bacterial disease of the nose that can sometimes infect the upper respiratory tract. It most commonly affects the nasal cavity—the nose is involved in 95–100 per cent of cases—however, it can also affect the nasopharynx, larynx, trachea, and bronchi.

Is a laryngocele cancerous?

Laryngocele may sometimes be the source of laryngeal cancers (3). These cancers can be particularly serious due to the deep invasion in the paraglottic space. In 1987, Birt reported that the ventricles in patients operated on for laryngeal cancer were significantly deeper than those with a normal larynx (12).

Is laryngocele life threatening?

In rare cases, the internal part of the laryngocele may cause rapid and complete airway obstruction with potentially fatal consequences. Although the incidence of internal laryngoceles is relatively rare, physicians should include this condition in the differential diagnosis of upper airway problems.

How is Rhinoscleroma diagnosed?

This chronic infectious disease of the upper respiratory tract is routinely diagnosed by means of tissue biopsy of the lesions. Nasal endoscopy reveals signs of all 3 stages of scleroma: catarrhal, granulomatous, and sclerotic. Bronchoscopy has a role in the early diagnosis of rhinoscleroma.

Is Rhinoscleroma infectious?

Rhinoscleroma is a chronic infectious disease of underdeveloped countries. The Medscape Drugs & Diseases article Klebsiella Infections may be of interest.

Is crooked nose normal?

Crooked noses are very common, whether they’re due to an old injury or a deviated septum. In fact, its estimated that about 80 percent of people have some form of deviated septum. Unless your crooked nose causes breathing problems, there’s no need for treatment.

How is laryngocele treated?

Conclusion: Endoscopic CO2 laser resection of internal laryngocele provides a reliable and cost-effective method that minimizes hospitalization and the need for tracheotomy. We believe that advances in the applications of laser in microlaryngosurgery will alter the traditional management of all type of laryngoceles.

What is supraglottic squamous cell carcinoma?

Early stage supraglottic squamous cell carcinoma (SSCC) is defined as T1 (tumor limited to one subsite of supraglottis with normal vocal cord mobility) or T2 (tumor invading more than one adjacent subsite of supraglottis or glottis or region outside of supraglottis), with no regional nodal spread [1].

What is the medical dictionary definition of scleroma?

(1) A nonspecific term for an indurated circumscribed subcutaneous or submucosal mass, in particular granulation tissue. (2) Rhinoscleroma, see there. Segen’s Medical Dictionary. © 2012 Farlex, Inc. All rights reserved. Induration, see there. A circumscribed indurated focus of granulation tissue in the skin or mucous membrane.

Where are scleromas most common in the world?

A scleroma can form when a chronic bacterial infection causes inflammation, swelling, and scarring in the tissues. They are most common in Central and South America, Africa, the Middle East, Asia, India, and Indonesia.

Which is part of the respiratory tract does scleroma affect?

Scleroma is a specific, chronic granulomatous condition of the upper respiratory tract that particularly affects the nose, classically, in all patients and the larynx in fewer patients, and less often the trachea and bronchi. 1

How does scleroderma affect structures beyond the skin?

In some people, scleroderma affects only the skin. But in many people, scleroderma also harms structures beyond the skin — such as blood vessels, internal organs and the digestive tract. Signs and symptoms vary, depending on which structures are affected.