What is the meaning of ossification?

What is the meaning of ossification?

Ossification: The process of creating bone, that is of transforming cartilage (or fibrous tissue) into bone. The verb corresponding to “ossification” is “ossify.” Cartilage becomes ossified as it is converted into bone.

What is ossification and when does it begin?

Parts of the skeleton form during the first few weeks after conception. By the end of the eighth week after conception, the skeletal pattern is formed in cartilage and connective tissue membranes and ossification begins. Bone development continues throughout adulthood.

What does ossification mean in health?

Ossification is the process in which cartilage is transformed into bone. Bone grows in three stages: first, tissue forms a mesh of collagen fibers, then the body creates a polysaccharide that acts like cement to hold the tissues together. Finally, calcium crystals salts are deposited to form bone.

What is ossification and why is it important?

It is the process by which bone tissue is created. Unlike the other process of bone creation— endochondral ossification—intramembranous ossification does not involve cartilage. It is also an essential process during the natural healing of bone fractures and the rudimentary formation of the bones of the head.

What causes ossification?

HO occurs after other injuries, too. HO has been known to occur in cases of traumatic brain injury, stroke, poliomyelitis, myelodysplasia, carbon monoxide poisoning, spinal cord tumors, syringomyelia, tetanus, multiple sclerosis, post total hip replacements, post joint arthroplasty, and after severe burns.

What is an example of ossification?

Ossify means to become bony. When a baby is born, some of their “bones” are actually soft cartilage, which allows for growth. As the child grows, these soft areas ossify into actual bone. The knee cap, for example, begins to ossify between ages 3 and 6.

How is ossification treated?

Usually, treatment will include gentle range of motion of the joints and some physical therapy. Your doctor may also prescribe medications to slow down or stop the abnormal growth of bone. When HO severely affects your movement or causes excruciating pain, surgery may be needed.

Can you reverse ossification?

Currently, “there’s no way to prevent it and once it’s formed, there’s no way to reverse it,” says Benjamin Levi, M.D., Director of the Burn/Wound/Regeneration Medicine Laboratory and Center for Basic and Translational Research in Michigan Medicine’s Department of Surgery.

What is the difference between calcification and ossification?

Ossification, or osteogenesis, is the process of bone formation by osteoblasts. Ossification is distinct from the process of calcification; whereas calcification takes place during the ossification of bones, it can also occur in other tissues.

How can you prevent ossification?

NSAIDs and radiation therapy are currently considered the gold standard in HO prevention [16, 17]. They act by modifying the microenvironment as they reduce the associated inflammatory process involved in HO formation.

What are the steps involved in ossification?

Place in order the steps involved in endochondral ossification. 1. Nutrient artery invades the perichondruim 2. Osteoclasts create a marrow cavity 3. Chondrocytes enlarge and calcify 4. Secondary ossification centers appear at epiphyses 5. Osteoblasts become active in the primary ossification center.

What is formed through a process called ossification?

Bone formation, also called ossification, process by which new bone is produced. Ossification begins about the third month of fetal life in humans and is completed by late adolescence.

What are the different types of ossification?

Ossification is the gradual transition from a fibrous or cartilaginous template to bone. This process takes place at different rates and is completed at different ages depending on the site of ossification. There are two distinct types of ossification, intermembranous and endochondral.

Which is the most common type of ossification?

In the first, and by far most common type, nonhereditary myositis ossificans (commonly referred to simply as “myositis ossificans”), calcifications occur at the site of injured muscle, most commonly in the arms or in the quadriceps of the thighs. The term myositis ossificans traumatica is sometimes used when the condition is due to trauma.