What is UPEP lab test for?

What is UPEP lab test for?

The urine protein electrophoresis (UPEP) test is used to estimate how much of certain proteins are in the urine.

What blood tests are done for myeloma?

Tests to Find Multiple Myeloma

  • Blood counts. The complete blood count (CBC) is a test that measures the levels of red cells, white cells, and platelets in the blood.
  • Blood chemistry tests.
  • Urine tests.
  • Quantitative immunoglobulins.
  • Electrophoresis.
  • Serum free light chains.
  • Beta-2 microglobulin.
  • Bone marrow biopsy.

What does an electrophoresis blood test show?

The serum protein electrophoresis (SPEP) test measures specific proteins in the blood to help identify some diseases. Proteins are substances made up of smaller building blocks called amino acids. Proteins carry a positive or a negative electrical charge, and they move in fluid when placed in an electrical field.

What causes increased gamma globulin?

Increased gamma globulin proteins may indicate: Blood cancers, including multiple myeloma, Waldenström macroglobulinemia, lymphomas, and chronic lymphocytic leukemias. Chronic inflammatory disease (for example, rheumatoid arthritis) Acute infection.

Why is Immunofixation done?

The immunofixation blood test is used to identify proteins called immunoglobulins in blood. Too much of the same immunoglobulin is usually due to different types of blood cancer. Immunoglobulins are antibodies that help your body fight infection.

What is an abnormal UPEP?

Interpreting the test results for UPEP is fairly straightforward: Globulins shouldn’t be present in your urine. Albumin levels should be below 5 milligrams per deciliter (mg/dL). Any amount of globulins — or more than 5 mg/dL of albumin — will be considered abnormal.

Does myeloma show up in a blood test?

For myeloma, you have blood tests and urine tests looking for an abnormal protein (the myeloma protein is called monoclonal protein, M-protein or paraprotein). Your blood sample is sent to the laboratory. A blood doctor looks at your sample under a microscope.

How is myeloma detected?

Specialized tests, such as fluorescence in situ hybridization (FISH) can analyze myeloma cells to identify gene mutations. Imaging tests. Imaging tests may be recommended to detect bone problems associated with multiple myeloma. Tests may include an X-ray, MRI, CT or positron emission tomography (PET).

What does a positive Immunofixation blood test mean?

Positive results from the test indicate the presence of abnormal Ig. This may suggest the existence of an underlying health condition, such as: an immune system disorder. multiple myeloma. Waldenstrom’s macroglobulinemia.

What does abnormal blood protein mean?

High blood protein (hyperproteinemia) is an increase in the concentration of protein in the bloodstream. High blood protein is not a specific disease or condition in itself, but it might indicate you have a disease. High blood protein rarely causes signs or symptoms on its own.

What are the symptoms of high globulin?

Investigating the cause of a raised globulin level

  • Bone pain (myeloma).
  • Night sweats (lymphoproliferative disorders).
  • Weight loss (cancers).
  • Breathlessness, fatigue (anaemia).
  • Unexplained bleeding (lymphoproliferative disorders).
  • Symptoms of carpal tunnel syndrome (amyloidosis).
  • Fever (infections).