Table of Contents
Why does Marfan cause myopia?
Most people with Marfan syndrome suffer from nearsightedness, or myopia, and abnormal curvature of the eye, or astigmatism. These can be notably high since the connective tissue defect can affect the cornea, lens, and growth of the eye.
How does Marfan syndrome affect the eyes?
Many people with Marfan syndrome will need glasses because they will develop myopia (nearsightedness) or have astigmatism (abnormal curvature of the eye). Patients with Marfan syndrome may also have a higher chance of developing cataracts, glaucoma, strabismus and retinal detachment.
Does Marfan syndrome affect facial features?
Individuals with Marfan syndrome may have several distinct facial features including a long, narrow skull (dolichocephaly), deep-set eyes (enophthalmos), an abnormally small jaw (micrognathia) that may be recessed farther back than normal (retrognathia), abnormally flat cheek bones (malar hypoplasia), and an abnormal …
What are 5 of the characteristics and symptoms of Marfan syndrome?
Marfan syndrome features may include:
- Tall and slender build.
- Disproportionately long arms, legs and fingers.
- A breastbone that protrudes outward or dips inward.
- A high, arched palate and crowded teeth.
- Heart murmurs.
- Extreme nearsightedness.
- An abnormally curved spine.
- Flat feet.
Can people with Marfan be short?
It affects males and females of all races and ethnicities. Children who have Marfan syndrome are usually tall and thin, with long arms, long double-jointed fingers, a short torso, and very long legs.
Is Marfan syndrome considered a disability?
If you are suffering from a severe case of Marfan syndrome and it has made you unable to work, you may be eligible to Social Security disability benefits. While people from all around the world, of all races and genders, can suffer from Marfan syndrome, the symptoms of the condition have a tendency to worsen with age.
What happens to the eye with Marfan syndrome?
About 60 percent of individuals who have Marfan syndrome have lens displacement from the center of the pupil (ectopia lentis). Individuals who have Marfan syndrome also have an increased risk for retinal detachment, glaucoma and early cataract formation.
How are connective tissue systems affected by Marfan syndrome?
Connective tissue is found all over the body and multiple organ systems may be affected in individuals with Marfan syndrome. The heart and blood vessels (cardiovascular), skeletal, and eye (ocular) systems are most often affected. Major symptoms include overgrowth of the long bones of the arms and legs,…
How many people in the world have Marfan syndrome?
Approximately seventy-five percent of individuals who have Marfan syndrome have a parent who also has the condition (inherited). Approximately 25 percent of individuals who have Marfan syndrome, have the condition as a result of a new (de novo) mutation.
Is there a genetic test for Marfan syndrome?
Genetic testing of the FBN1 gene identifies 70 – 93 percent of the mutations and is available in clinical laboratories. However patients negative for the test for gene mutation should be considered for evaluation for other conditions that have similar features of Marfan syndrome such as Dietz syndrome, Ehlers Danlos syndrome, and homocystinura.